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|Transcriptional Factors And Regulators|
All the cellular processes in living cells such as growth, development, morphogenesis and cellular differentiation are a product of gene expression programs involving complicated transcriptional regulation of several genes. This process of transcriptional regulation is tightly controlled and coordinated by proteins called transcriptional regulators.
|Folate Receptor 4 (FR4)|
Folates play an important role in protein and nucleic acid biosynthesis and are particularly recognized for their roles in spinal canal and brain development during early pregnancy.
Neuropilin-1 (Nrp-1) was recently identified as a possible surface marker for naturally occurring CD4+CD25+ regulatory T cells and is constitutively expressed on the cell irrespective of its activation status.
|A Functional Contributor to Cancer Metastatic Potential|
Tumor metastasis plays a key role in assessing treatment strategies and an important factor in determining patient prognosis. Not surprisingly, significant effort has been focused on elucidating the molecular basis behind tumor metastasis.
|In Search of Putative FOXP3+ Cell Surface Markers|
Flow cytometric analysis of intracellular FOXP3 (IMG-5802D) and cell surface FR4 with clone 12A5 (IMG-6217C) (left) and clone TH6 (IMG-6218C) (right) at 0.06 ug/10^6 mouse splenocytes.
|TLR10- cluster of differentiation 290|
Toll-like receptor 10 (TLR10) often known as CD290 (cluster of differentiation 290), is the most recently identified human homolog of the Drosophila TOLL protein.
|TLR9- cluster of differentiation 289|
Toll-like receptor 9 (TLR9) often known as CD289 (cluster of differentiation 289), is a member of the Toll-like receptor family that recognizes pathogen-associated molecular pattern.
|TLR8- cluster of differentiation 288|
Toll-like receptor 8 (TLR8) often designated as CD288 (cluster of differentiation 288) is a member of evolutionarily conserved Toll-like receptor family which are critical parts of the evolutionarily conserved innate immune system.
|TLR7- cluster of differentiation 287|
Toll-like receptor 7 (TLR7), is an immune gene possessed by humans, other mammals and additionally in avian species playing a significant role in initiating antiviral immune responses.
|TLR6- cluster of differentiation 286|
Toll-like receptor 6 (TLR6) often designated as CD286 (cluster of differentiation 286), is a member of the Toll-like receptor family, a highly conserved series of ancient innate immune pattern recognition receptors.
|TLR5- cluster of differentiation 285|
Toll-like receptor 5 (TLR5), a member of the evolutionarily conserved Toll-like receptor family, has evolved to permit mammals specifically to detect flagellated bacterial pathogens.
|TLR4- cluster of differentiation 284|
Toll-like receptor 4 (TLR4) often designated as CD284 (cluster of differentiation 284) is a class I transmembrane receptor belonging to the large homologous family of Toll like receptors.
|TLR3- cluster of differentiation 283|
Toll-like receptor 3 (TLR3) often designated as CD283 (cluster of differentiation 283) is a type I transmembrane receptor protein.
|TLR2- cluster of differentiation 282|
Toll-like receptor 2 (TLR2), often designated as CD282 (cluster of differentiation 282) is a type I transmembrane protein belonging to the large homologous family of Toll like receptors.
|TLR1- cluster of differentiation 281|
Toll-like receptor 1 (TLR1) often designated as CD281 (cluster of differentiation 281), a member of the Toll-like receptor family recognizes pathogen-associated molecular pattern with specificity for gram-positive bacteria.
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